Matsue Y, Okuma T
Tohoku J Exp Med. 1984 Jul;143(3):345-9. doi: 10.1620/tjem.143.345.
Time relationship between the horizontal smooth pursuit eye movement (SPEM) and tracking target in the leftward or rightward tracking was investigated in 28 normal and 25 chronic schizophrenic subjects. Normal subjects were more liable to show a relative advance of SPEM in relation to the target in the leftward pursuit than in the rightward pursuit. These findings suggest that the spatial task such as SPEM depends more on the right hemispheric function in normal subjects. On the other hand, many of schizophrenic subjects showed a relative advance of SPEM to the target in the rightward pursuit. These findings suggest the dominance of the left hemispheric function in eye tracking tasks in schizophrenic subjects. The finding in the present study would support the hypothesis of the left hemispheric overactivation in the schizophrenic patients.
在28名正常受试者和25名慢性精神分裂症患者中，研究了向左或向右追踪时水平平稳跟踪眼动（SPEM）与跟踪目标之间的时间关系。正常受试者在向左追踪时比向右追踪时更易出现SPEM相对于目标的相对提前。这些发现表明，诸如SPEM之类的空间任务在正常受试者中更多地依赖于右半球功能。另一方面，许多精神分裂症患者在向右追踪时表现出SPEM相对于目标的相对提前。这些发现表明精神分裂症患者在眼动追踪任务中左半球功能占主导地位。本研究中的发现将支持精神分裂症患者左半球过度激活的假说。
