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[支气管哮喘和过敏性鼻炎患者对霉菌致敏性增加的发生率检测]

[Detection of the incidence of increased sensitization to molds in patients with bronchial asthma and allergic rhinitis].

作者信息

Kautz S, Bergmann I, Dehnert I, Fischer J F, Frenzel K, Leupold W, Meister W, Schuster R, Zochert J

出版信息

Z Erkr Atmungsorgane. 1984;163(1):24-31.

PMID:6485392
Abstract

The incidence of sensibilization against extracts of moulds produced by VEB SSW Dresden was investigated by intracutaneous tests in 354 persons (controls and patients - adults and children - with bronchial asthma and allergic rhinitis). Even in the nonallergic controls the tests were positive in 20-30%. Patients with asthma and rhinitis were significantly more often positive than controls with Mucor, Cladosporium and mixed-mould. There was no difference between the groups with Aspergillus and Penicillium. Testing with extract of mixed-mould is not effective. Positive results with the individual moulds were not excluded although the test with mixed-mould was negative. There was no essential difference in the incidence of sensibilization between adults and children with bronchial asthma using mould extracts of VEB SSW Dresden.

摘要

通过皮内试验对354人(对照组以及患有支气管哮喘和过敏性鼻炎的患者——包括成人和儿童)进行了研究,以调查对德国德累斯顿VEB SSW生产的霉菌提取物的致敏发生率。即使在非过敏对照组中,试验呈阳性的比例也为20% - 30%。哮喘和鼻炎患者对毛霉、枝孢菌和混合霉菌呈阳性的比例显著高于对照组。曲霉和青霉组之间没有差异。使用混合霉菌提取物进行检测无效。尽管混合霉菌检测呈阴性,但不排除个体霉菌检测呈阳性的结果。使用德国德累斯顿VEB SSW的霉菌提取物时,成人和儿童支气管哮喘患者的致敏发生率没有本质差异。

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