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[对德国裔复发性良性口疮患者和白塞病患者进行的人类白细胞抗原分型]

[HLA typing in patients of German origin with recurrent benign aphthosis and Behçet's disease].

作者信息

Djawari D, Lang B, Hornstein O P

出版信息

Z Hautkr. 1984 Aug 1;59(15):1005-9.

PMID:6485449
Abstract

HLA-pattern was analysed in 60 patients with recurrent benign aphthosis (RBA), in another 14 suffering from Behçet's disease (BD) and in 200 healthy individuals, all of German origin. High prevalence rates of HLA-A2, HLA-B5 and HLA-Cw3 haplotypes were found in patients with RBA, yet significant only for HLA-Cw3 (p = 0.01). HLA-B5 was shown in none but two German patients with BD. These results are discussed with particular regard to reports on racial differences of HLA-patterns in the populations of several continents including patients with aphthous disorders.

摘要

对60例复发性良性口疮(RBA)患者、另外14例白塞病(BD)患者以及200名均为德国血统的健康个体进行了HLA分型分析。在RBA患者中发现HLA - A2、HLA - B5和HLA - Cw3单倍型的高流行率,但仅HLA - Cw3具有统计学意义(p = 0.01)。仅在两名德国BD患者中发现了HLA - B5。结合关于包括口疮性疾病患者在内的几大洲人群中HLA分型种族差异的报告,对这些结果进行了讨论。

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