Rozaeva N R, Bichurrina M A, Volgarev A P, Fridman E A
Zh Mikrobiol Epidemiol Immunobiol. 1984 Aug(8):97-101.
The administration of inactivated chromatographic influenza vaccine to mice in three injections induced the formation of the pronounced clone of antigen-reactive lymphocytes, detected in the leukocyte blast transformation test. Slight fluctuations in the phytohemagglutinin level and lipopolysaccharide response in mice subjected to multiple immunization with the inactivated vaccine indicated that this preparation produced no damaging effect on the T- and B-lymphocyte populations.
对小鼠分三次注射灭活的层析流感疫苗，在白细胞转化试验中可诱导出明显的抗原反应性淋巴细胞克隆形成。用灭活疫苗对小鼠进行多次免疫后，其植物血凝素水平和脂多糖反应有轻微波动，这表明该制剂对T淋巴细胞和B淋巴细胞群体没有损害作用。
