Miyake K, Asakura M, Kobayashi H
Am J Ophthalmol. 1984 Oct 15;98(4):451-5. doi: 10.1016/0002-9394(84)90130-2.
We used slit-lamp fluorophotometry to evaluate the influence of various intraocular lens fixation sites on the blood-aqueous barrier in 106 eyes. After an average follow-up period of 1.1 years, eyes with anterior chamber lenses with closed or rectangular loops had a significantly higher concentration of fluorescein than did eyes with other types of implants (P less than .1 to P less than .001). In eyes with posterior chamber lenses, those with ciliary sulcus fixation had a significantly higher concentration of fluorescein than did those with intracapsular fixation (P less than .02). Compared with aphakic eyes without implants, eyes with any implant other than posterior chamber lenses with intracapsular fixation had significantly higher fluorescein concentrations (P less than .02 to P less than .001). These results indicated that the flexibility and the intraocular location of the lens loops are significant factors in securing the integrity of the blood-aqueous barrier of pseudophakic eyes. Posterior chamber lenses with intracapsular fixation caused the least trauma to the blood-aqueous barrier.
我们采用裂隙灯荧光光度法评估了106只眼中不同人工晶状体固定部位对血-房水屏障的影响。平均随访1.1年后，采用闭合或矩形袢的前房型人工晶状体眼的荧光素浓度显著高于其他类型植入物眼（P＜0.1至P＜0.001）。在植入后房型人工晶状体的眼中，睫状沟固定眼的荧光素浓度显著高于囊内固定眼（P＜0.02）。与未植入人工晶状体的无晶状体眼相比，除囊内固定的后房型人工晶状体外，其他任何植入物眼的荧光素浓度均显著更高（P＜0.02至P＜0.001）。这些结果表明，晶状体袢的柔韧性和眼内位置是确保人工晶状体眼血-房水屏障完整性的重要因素。囊内固定的后房型人工晶状体对血-房水屏障造成的损伤最小。
