Tsuboi S, Tsujioka M, Kusube T, Kojima S
Institute of Ophthalmology, Tane Memorial Eye Hospital, Osaka, Japan.
Arch Ophthalmol. 1992 Aug;110(8):1124-7. doi: 10.1001/archopht.1992.01080200104035.
Permeability across the blood-aqueous barrier to fluorescein was estimated fluorophotometrically in pseudophakic eyes for which a continuous circular capsulorhexis was performed. The permeability index was significantly higher in the in-the-bag fixations than in the out-of-the-bag fixations at 3 and 6 months after surgery, when only bilateral cases were enrolled. Damage to the barrier in eyes with the in-the-bag fixations was attributable to the broad attachment of optics to the anterior capsule, because a positive linear regression was obtained between the permeability index and the doughnut-shaped contact area in eyes with the in-the-bag fixations. The permeability index in eyes with the in-the-bag fixations was as low as that in eyes with the out-of-the-bag fixations when the contact area was small. These results indicate an unfavorable effect of the in-the-bag fixation with broad contact of the optics with the anterior capsule and, thus, suggest either an in-the-bag fixation with a large capsulorhexis or an out-of-the-bag fixation.
通过荧光光度法估计了在进行连续环形撕囊术的人工晶状体眼中，荧光素透过血-房水屏障的渗透率。仅纳入双侧病例时，术后3个月和6个月，囊袋内固定眼的渗透率指数显著高于囊袋外固定眼。囊袋内固定眼的屏障损伤归因于光学部与前囊的广泛附着，因为在囊袋内固定眼中，渗透率指数与甜甜圈形接触面积之间获得了正线性回归。当接触面积较小时，囊袋内固定眼的渗透率指数与囊袋外固定眼一样低。这些结果表明囊袋内固定且光学部与前囊广泛接触具有不利影响，因此，建议采用大撕囊的囊袋内固定或囊袋外固定。
