Ohrloff C, Schalnus R, Rothe R, Spitznas M
University Eye Hospital Frankfurt, West Germany.
J Cataract Refract Surg. 1990 Mar;16(2):198-201. doi: 10.1016/s0886-3350(13)80730-4.
Clinical observations have shown that an intact posterior capsule between aqueous and vitreous may function as a barrier to low and high molecular weight substances, e.g., prostaglandins or the angiogenic factor. To determine if this protective barrier breaks down after posterior capsulotomy, we examined the distribution of fluorescein in human eyes after intracapsular cataract extraction (ICCE), extracapsular cataract extraction (ECCE) and intraocular lens (IOL) implantation with capsulotomy, and ECCE and IOL implantation without capsulotomy in 12 patients each. After ICCE and after ECCE and IOL implantation with capsulotomy, diffusion of fluorescein into the vitreous showed similar values. These values were significantly higher than those obtained in patients after ECCE or ECCE and IOL implantation without capsulotomy. This leads us to believe that an intact posterior capsule prevents the diffusion of soluble substances.
临床观察表明，房水和玻璃体之间完整的后囊可作为低分子量和高分子量物质（如前列腺素或血管生成因子）的屏障。为了确定后囊切开术后这种保护屏障是否会被破坏，我们检查了12例接受囊内白内障摘除术（ICCE）、囊外白内障摘除术（ECCE）及切开后囊植入人工晶状体（IOL）的患者，以及12例接受ECCE及未切开后囊植入IOL的患者眼中荧光素的分布情况。ICCE后以及ECCE及切开后囊植入IOL后，荧光素向玻璃体的扩散情况相似。这些数值显著高于ECCE后或ECCE及未切开后囊植入IOL的患者所测得的数值。这使我们相信完整的后囊可防止可溶性物质的扩散。
