Morse D E, Cova J L
Anat Rec. 1984 Sep;210(1):125-32. doi: 10.1002/ar.1092100115.
Cells laden with pigment granules are described in the leptomeningeal tissues of the cat and kitten. These cells can be identified consistently by gross observation following vascular perfusion. The fusiform or stellate pigmented cells are most often found in association with the outermost layers of the arteries of the subarachnoid space. They are typically separated from the cerebrospinal fluid by an attenuated layer of pial cells. Vessels that are described as having pigmented cells along their course are the anterior and posterior cerebellar; the anterior, middle, and posterior cerebral; and the basilar. Electron microscopic studies confirm the presence of abundant pigment granules. The pigment granules are the predominant component of the cytoplasm. Few organelles are demonstrable except for a large central nucleus. The data provide support for the concept of neural crest contribution to leptomeningeal structures. Identification of this isolated, easily defined population of melanocytes may provide a model for further studies of neural crest distribution as well as experimental approaches to melanogenesis and melanoma production and control.
在猫和小猫的软脑膜组织中发现了充满色素颗粒的细胞。通过血管灌注后的大体观察，可以始终如一地识别出这些细胞。梭形或星形色素细胞最常出现在蛛网膜下腔动脉的最外层。它们通常被一层变薄的软膜细胞与脑脊液隔开。被描述为沿其行程有色素细胞的血管有小脑前动脉和后动脉；大脑前动脉、中动脉和后动脉；以及基底动脉。电子显微镜研究证实了大量色素颗粒的存在。色素颗粒是细胞质的主要成分。除了一个大的中央核外，几乎没有可显示的细胞器。这些数据为神经嵴对软脑膜结构的贡献这一概念提供了支持。识别这种孤立的、易于定义的黑素细胞群体可能为进一步研究神经嵴分布以及黑素生成、黑色素瘤产生和控制的实验方法提供一个模型。
