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明胶海绵与32%右旋糖酐70联合使用预防猪腹腔粘连的实验研究

Prevention of peritoneal adhesions by the combined use of spongostan and 32% dextran 70: an experimental study in pigs.

作者信息

Luengo J, van Hall E V

出版信息

Fertil Steril. 1978 Apr;29(4):447-50. doi: 10.1016/s0015-0282(16)43223-1.

DOI:10.1016/s0015-0282(16)43223-1
PMID:648648
Abstract

Twenty female pigs underwent laparotomy during which transection of both uterine horns and wedge resection of both ovaries were performed with a standard technique. Following the injuries a mixture of Spongostan and 32% dextran 70 was applied only to the lesions on the right side. Three weeks after surgery another laparotomy was performed and the degree of adhesion formation was recorded. A marked reduction in degree and extent of adhesions was observed on the treated side as compared with the control side. The possible advantages of a compound that can be applied locally and has hemostatic properties as well are discussed.

摘要

20只雌性猪接受了剖腹手术,术中采用标准技术对双侧子宫角进行横断,并对双侧卵巢进行楔形切除。损伤后,仅在右侧病变处应用明胶海绵和32%右旋糖酐70的混合物。术后三周再次进行剖腹手术,并记录粘连形成的程度。与对照侧相比,治疗侧粘连的程度和范围明显减轻。文中讨论了一种可局部应用且具有止血特性的化合物可能具有的优势。

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Fertil Steril. 1978 Apr;29(4):447-50. doi: 10.1016/s0015-0282(16)43223-1.
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引用本文的文献

1
Surgical reversal of tubal ligation.输卵管结扎术的手术复通。
Can Fam Physician. 1979 May;25:579-82.
2
General surgeons' attitudes to the treatment and prevention of abdominal adhesions.普通外科医生对腹部粘连治疗与预防的态度。
Ann R Coll Surg Engl. 1993 Mar;75(2):123-8.