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泰国北部人群中的缺铁情况:通过血浆铁蛋白测定研究铁补充剂的效果。

Iron deficiency in a Northern Thai population: the effects of iron supplements studied by means of plasma ferritin estimations.

作者信息

Linpisarn S, Thanangkul O, Suwanraj C, Kaewvichit R, Kricka L J, Whitehead T P

出版信息

Ann Clin Biochem. 1984 Jul;21 ( Pt 4):268-74. doi: 10.1177/000456328402100407.

Abstract

Iron deficiency is a common problem, particularly in developing countries, but traditional laboratory methods of detecting this condition are unreliable. The prevalence of iron deficiency in a Northern Thai population (pre-school, school children, adult women) has been assessed by means of plasma ferritin concentrations. The results were compared with prevalences based on blood haemoglobin concentrations. Estimations of prevalences based on plasma ferritin values were 10-24% in non-vegetarian and 49-71% in vegetarian groups, whilst those based on blood haemoglobin were 11-21% (non-vegetarian) and 24-50% (vegetarian). Dietary supplementation with iron produced dramatic rises in plasma ferritin in all of the groups studied. The effects on blood haemoglobin concentration and haematocrit were less marked. These results highlight the extent of iron deficiency in a Thai population and demonstrate the sensitivity of plasma ferritin as a test for detecting this condition and assessing the response to dietary supplementation.

摘要

缺铁是一个常见问题,在发展中国家尤为如此,但传统的检测这种情况的实验室方法并不可靠。泰国北部人群(学龄前儿童、在校学生、成年女性)的缺铁患病率已通过血浆铁蛋白浓度进行评估。结果与基于血红蛋白浓度的患病率进行了比较。基于血浆铁蛋白值估计的患病率在非素食组为10%-24%,素食组为49%-71%,而基于血红蛋白的患病率在非素食组为11%-21%,素食组为24%-50%。在所研究的所有组中,补充铁剂后血浆铁蛋白显著升高。对血红蛋白浓度和血细胞比容的影响则不太明显。这些结果突出了泰国人群中铁缺乏的程度,并证明了血浆铁蛋白作为检测这种情况和评估膳食补充反应的一项检测指标的敏感性。

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