Ooshika Y, Umesaki N, Sako H, Kawabata M, Sugana T
Gan To Kagaku Ryoho. 1984 Oct;11(10):2177-84.
The effects of an anabolic steroid on the immune activity and clinical condition of patients with cancer of the uterine cervix were studied. The effects of the steroid on tumor growth were also studied in animals. The results obtained demonstrated that the anabolic steroid (1) enhanced the activity of macrophages and cell-mediated immune activity, (2) reduced the incidence of post-operative infection, (3) reduced pose-operative loss of weight of patients due to the intrinsic anabolic activity of the steroid, and (4) did not exert any influence on tumor growth. Judging from these results, administration of the anabolic steroid would appear to be effective for the improvement of the general condition of cancer patients following surgery or in terminal cases.
研究了一种合成代谢类固醇对子宫颈癌患者免疫活性和临床状况的影响。还在动物身上研究了该类固醇对肿瘤生长的影响。获得的结果表明，合成代谢类固醇（1）增强了巨噬细胞的活性和细胞介导的免疫活性，（2）降低了术后感染的发生率，（3）由于类固醇固有的合成代谢活性，减少了患者术后体重的减轻，并且（4）对肿瘤生长没有任何影响。从这些结果来看，给予合成代谢类固醇似乎对改善癌症患者术后或晚期的总体状况有效。
