Friedman S J, Su W P
Arch Dermatol. 1984 Oct;120(10):1329-36.
Twenty-two patients with 31 leg ulcers of various causes received local wound management consisting of the application of an adhesive hydrocolloid (HC) occlusive dressing (DuoDerm). Group 1 comprised 15 patients (11 outpatients) with 19 ulcers. Approximately two thirds (12/19) of the ulcers healed when treated solely with the HC dressing; mean treatment time was 57 days. Group 2 comprised seven hospitalized patients with at least two leg ulcers of similar size and distribution. The 20 ulcers in the seven patients were treated with either mild topical antimicrobial wet dressings (Sweitzer's 1:32 solution) or HC dressings, with each patient serving as his own "control." All 20 ulcers healed; the average time to healing was 44 days with HC dressing and 42 days with wet dressing management. Most of the patients reported convenience in management and substantial relief of pain with the use of HC dressings.
22例患有31处各种病因导致的腿部溃疡的患者接受了局部伤口处理,包括使用粘性水胶体(HC)封闭敷料(多爱肤)。第1组包括15例患者(11例门诊患者),有19处溃疡。约三分之二(12/19)的溃疡仅用HC敷料治疗后愈合;平均治疗时间为57天。第2组包括7例住院患者,患有至少两处大小和分布相似的腿部溃疡。这7例患者的20处溃疡用轻度局部抗菌湿敷料(斯韦策1:32溶液)或HC敷料治疗,每位患者自身作为“对照”。所有20处溃疡均愈合;使用HC敷料愈合的平均时间为44天,使用湿敷料处理的平均时间为42天。大多数患者报告使用HC敷料管理方便且疼痛明显减轻。