LeLiever W C, Bailey B J, Griffiths C
Arch Otolaryngol. 1984 Nov;110(11):748-51. doi: 10.1001/archotol.1984.00800370050012.
Twenty-two patients with nasal septal carcinoma have been treated at the University of Texas Medical Branch, Galveston, during the 18-year period from 1961 to 1979. Squamous cell carcinoma of the nasal septum was found in 18 patients (82%), with single instances of reticulum cell sarcoma, basal cell carcinoma, histiocytic lymphoma, and transitional cell carcinoma. One of the squamous cell carcinoma group had palpable cervical metastasis at diagnosis, with metastatic neck disease developing in eight patients from three to 25 months after treatment. Squamous cell carcinoma of the nasal septum is aggressive and often undertreated. Our experience suggests that patients with septal carcinoma of any size should be treated by wide surgical excision (via lateral rhinotomy) and irradiation to the primary site and neck. Control of the primary tumor was achieved in 17 of 18 patients, with neck control in ten patients. The five-year absolute survival rate for squamous cell carcinoma of the nasal septum was 66%.
1961年至1979年的18年间，得克萨斯大学加尔维斯顿医学分校收治了22例鼻中隔癌患者。18例（82%）为鼻中隔鳞状细胞癌，还有1例网状细胞肉瘤、1例基底细胞癌、1例组织细胞淋巴瘤和1例移行细胞癌。鳞状细胞癌组中有1例在诊断时可触及颈部转移，另有8例患者在治疗后3至25个月出现颈部转移性疾病。鼻中隔鳞状细胞癌具有侵袭性，且常常治疗不足。我们的经验表明，任何大小的鼻中隔癌患者均应接受广泛手术切除（经鼻侧切开术），并对原发部位和颈部进行放疗。18例患者中有17例实现了原发肿瘤的控制，10例患者实现了颈部控制。鼻中隔鳞状细胞癌的五年绝对生存率为66%。
