Peek J C, Godfrey B, Matthews C D
Br J Obstet Gynaecol. 1984 Oct;91(10):1019-24. doi: 10.1111/j.1471-0528.1984.tb03681.x.
The pregnancy rates after artificial insemination by donor semen (AID) have been compared with pregnancy rates in normal fertile women to assess the efficiency of AID. To do this, the curve y = a(1-(1-b)x) was fitted to life-tabled cumulative pregnancy rates. The equation describes a model in which the parameter a is the proportion of women who are potentially fertile under the conditions of treatment, and in which the parameter b is the pregnancy rate per cycle (or fecundity) of these fertile women. For 259 AID patients with no previous pregnancy a was 65% while for 57 AID patients with a previous pregnancy after AID 'a' was 99.9%. The values of b were similar for the two groups of patients, being 20% and 22% respectively. Women without fertility problems who had become pregnant after discontinuing oral contraception provided the reference group. Since only pregnant women were selected, a was 100% by definition. The values of b for the reference group were 22% for 100 primigravid women and 20% for 100 multigravid women. Only 65% of the AID patients were potentially fertile with AID, but those that were fertile became pregnant at the same rate as normal women who discontinued oral contraception.
通过比较供体精液人工授精(AID)后的妊娠率与正常育龄妇女的妊娠率,来评估AID的效率。为此,将曲线y = a(1-(1-b)x)拟合到生命表累积妊娠率。该方程描述了一个模型,其中参数a是在治疗条件下可能受孕的女性比例,参数b是这些可孕女性每个周期的妊娠率(或生育力)。对于259名既往未孕的AID患者,a为65%;而对于57名既往有过AID后妊娠的AID患者,“a”为99.9%。两组患者的b值相似,分别为20%和22%。停止口服避孕药后怀孕的无生育问题女性作为参照组。由于仅选择了已怀孕的女性,根据定义a为100%。参照组中,100名初产妇的b值为22%,100名经产妇的b值为20%。AID患者中只有65%在AID治疗下可能受孕,但那些可孕的患者怀孕的概率与停止口服避孕药的正常女性相同。