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[急性呼吸衰竭综合征实验模型中心脏动力学与肺气体交换的相互关系]

[Interrelation of cardiodynamics and pulmonary gas exchange in an experimental model of the acute respiratory failure syndrome].

作者信息

Rogatskiĭ G G

出版信息

Biull Eksp Biol Med. 1984 Sep;98(9):273-5.

PMID:6487779
Abstract

Experiments were made on 30 dogs with lung contusion or injury to the chest wall. Eighteen animals demonstrated acute progressive arterial hypoxemia which proved to be fatal. Apart from the symptoms pointing to the development of gas exchange abnormalities, one could observe progressive impairment of myocardial function. A close correlation was established between pulmonary gas exchange and myocardial contractility. Myocardial dysfunction is regarded as one of the leading components in the pathogenesis of acute respiratory insufficiency in chest injury.

摘要

对30只患有肺挫伤或胸壁损伤的狗进行了实验。18只动物出现了急性进行性动脉低氧血症,最终被证明是致命的。除了指向气体交换异常发展的症状外,还可观察到心肌功能的进行性损害。肺气体交换与心肌收缩力之间建立了密切的相关性。心肌功能障碍被认为是胸部损伤后急性呼吸功能不全发病机制中的主要因素之一。

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