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[Regulation of the excisional repair system in in vitro-cultured human cells by measles viruses depending on their attenuation].

作者信息

Antonenko S V, Chekova V V, Nadgornaia N I, Sinel'shchikova T A, Zasukhina G D

出版信息

Biull Eksp Biol Med. 1984 Sep;98(9):298-301.

PMID:6487787
Abstract

The effect of measles viruses (attenuated strain L-16 and virulent strain Edmonston) was studied in human cells (line L-41) according to the criteria of repair: excision of thymine dimers, repair replication of DNA and resynthesis of DNA breaks induced by UV-irradiation. Reproduction of attenuated measles virus in cells was accompanied with stimulation of excision of thymine dimers and repair replication of DNA in contradistinction to mild virus. This phenomenon depended on multiplicity of infection.

摘要

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