Domenichelli B, Scabbia E, Mazzari M, Manzoli U
G Ital Cardiol. 1978;8(4):436-45.
The influence of KCl on different electrophysiologic parameters and myocardial stimulation threshold (MST) are considered in 9 patients with cardiac pacemaker. Reduction of MST during the diastolic period and the supernormal phase of excitability (SNP), depression of automaticity and slight bradycardia have been observed. The Authors, on the basis of kaliemia values and electrophysiologic parameters, emphasize the improvement of myocardial responsiveness when kaliemia does not exceed 6.5 mEq/l. The electrophysiologic effects of KCl are compared with those obtained in vitro on the transmembrane potential. Therapeutic effects for the treatment of arrhythmias and exit block in patients with cardiac pacemakers are considered.
研究了氯化钾对9例心脏起搏器患者不同电生理参数及心肌刺激阈值(MST)的影响。观察到舒张期和超常期兴奋性(SNP)期间MST降低、自律性抑制及轻度心动过缓。作者根据血钾值和电生理参数强调,当血钾不超过6.5 mEq/L时心肌反应性得到改善。将氯化钾的电生理效应与体外跨膜电位实验结果进行了比较。还探讨了氯化钾对心脏起搏器患者心律失常和传出阻滞的治疗作用。