Bolte A, Zippel H H, Berendes R, Meyer V
Geburtshilfe Frauenheilkd. 1978 Apr;38(4):260-9.
By means of ultrasound and fetal electrocardiography the diagnosis of twin pregnancies can be made prenatally without any reservation; the diagnosis is even possible in the first half of pregnancy. Comparative analysis of two approximately equal collectives of in all 602 twin pregnancies--1,45% of all births in the years 1955-1975 at the University Clinic for Gynecology and Obstetrics of the University of Cologne--revealed a better prognosis concerning the course of pregnancy and the new-born by prenatal diagnosis. The earliest possible diagnosis of twins, resulting in more intense clinical observation--and occasional clinical treatment--facilitated a significantly longer duration of pregnancy, leading to a higher percentage of mature twins. Whereas the total number of obstetric operations was reduced because of prenatal diagnosis, selection of highrisk cases led to a distinct increase in Caesarian sections. The prolongation of pregnancy, the higher birth weights and better maturity attained, were accompanied by decrease in perinatal mortality and in improvement in the Apgar-index of the newborn in that collective, in which prenatal diagnosis was achieved.
借助超声和胎儿心电图检查,可毫无保留地在产前做出双胎妊娠的诊断;甚至在妊娠前半期即可做出诊断。对科隆大学妇产科大学诊所1955 - 1975年期间所有602例双胎妊娠(占所有分娩的1.45%)这两个大致相等的群体进行比较分析发现,产前诊断对于妊娠过程和新生儿的预后更佳。尽早诊断双胎,从而进行更密切的临床观察——以及偶尔的临床治疗——使妊娠持续时间显著延长,成熟双胎的比例更高。虽然由于产前诊断产科手术总数减少,但高危病例的选择导致剖宫产明显增加。在实现产前诊断的群体中,妊娠延长、出生体重增加和成熟度提高,同时围产期死亡率降低,新生儿阿氏评分改善。