Günthard H P
Geburtshilfe Frauenheilkd. 1978 Apr;38(4):275-80.
In about 65% of the 258 twin births which occurred at the University Gynaecological Hospital, Zürich, from 1966 to 1976, it was possible to diagnose the twin pregnancy before the birth of the first twin. Twin pregnancy could be diagnosed in 96.2% of all the cases before the birth of the first twin, after routine ultrasound diagnosis of pregnancy had been introduced. Prerequisite of optimal treatment of pregnancy is a very early diagnosis which is only possible by widest use of ultrasound investigation technique. The rate of premature births was reduced from 48.0% to 27.3% by means of complete rest in bed and prophylactic tocolysis with a betamimetic from the 32nd to the 37th week of pregnancy. At the same time, the number of underweight children below 2.500 g was reduced by means of this treatment from 60.1% to 34.1%. It seems to be an undisputable fact that prolonged hospitalization in the last three months of pregnancy will improve the prognosis.
1966年至1976年期间,苏黎世大学妇科医院共发生258例双胎分娩,其中约65%的病例在第一个胎儿出生前就能够诊断出双胎妊娠。在引入常规超声妊娠诊断后,96.2%的病例在第一个胎儿出生前能够诊断出双胎妊娠。妊娠最佳治疗的前提是非常早期的诊断,而这只有通过广泛使用超声检查技术才有可能实现。通过在妊娠第32至37周卧床休息并使用β-拟交感神经药物进行预防性宫缩抑制,早产率从48.0%降至27.3%。同时,通过这种治疗,体重低于2500克的低体重儿数量从60.1%降至34.1%。妊娠最后三个月延长住院时间似乎将改善预后,这似乎是一个无可争议的事实。