Kranzfelder D, Mestwerdt W
Geburtshilfe Frauenheilkd. 1978 Apr;38(4):289-91.
Report on a 33 years old para 4, who developed invasive squamous cell carcinoma of the cervix three years after cryosurgery for a large ectopy of the ectocervix. The carcinoma developed under an intact layer of normal superficial epithelium. The pap smears were negative at yearly intervals until a positive smear was obtained from a small iodinenegative area. Cases following cryosurgery appear to require careful follow-ups.
关于一名33岁经产4次女性的报告,该女性在宫颈外口大片外翻行冷冻治疗三年后发生了宫颈浸润性鳞状细胞癌。癌肿在完整的正常表层上皮下发展。每年的巴氏涂片检查均为阴性,直到从小的碘不着色区域获得阳性涂片。冷冻治疗后的病例似乎需要仔细随访。