Sevin B U, Ford J H, Girtanner R D, Hoskins W J, Ng A B, Nordqvist S R, Averette H E
Obstet Gynecol. 1979 Apr;53(4):465-71.
Eight cases of invasive cervical carcinoma detected after cryotherapy for presumably noninvasive cervical lesions are reported. Three of these patients died from their disease less than 2 years following definitive therapy. The potential dangers of a less-than-optimal work-up of patients prior to freezing are analyzed and discussed in detail. Possible explanations for failures of cryotherapy are discussed, and guidelines for prevention of failures are presented.
本文报告了8例在对疑似非侵袭性宫颈病变进行冷冻治疗后检测出侵袭性宫颈癌的病例。其中3例患者在确定性治疗后不到2年因疾病死亡。详细分析并讨论了在冷冻治疗前对患者进行欠佳检查的潜在风险。讨论了冷冻治疗失败的可能原因，并提出了预防失败的指南。
