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人脐静脉平滑肌细胞缺乏C3b受体和免疫球蛋白G的Fc段受体。

Human umbilical cord vein smooth muscle cells lack receptors for C3b and the Fc portion of immunoglobulin G.

作者信息

Shingu M, Nobunaga M, Yoshida K

出版信息

Clin Immunol Immunopathol. 1984 Nov;33(2):282-6. doi: 10.1016/0090-1229(84)90082-5.

DOI:10.1016/0090-1229(84)90082-5
PMID:6488593
Abstract

Under apparently normal conditions, the smooth muscle cells obtained from veins of human umbilical cord do not possess receptors for C3b or the Fc portion of IgG. These receptors were not expressed even after exposure to neutrophil lysate or a superoxide-generating system. The lack of these receptors argues against the possibility that smooth muscle cells participate in the pathogenesis of immune complex diseases through binding of C3b or Fc fragments.

摘要

在表面正常的情况下,从人脐带静脉获取的平滑肌细胞不具备C3b或IgG的Fc段受体。即使暴露于中性粒细胞裂解物或超氧化物生成系统后,这些受体也未表达。缺乏这些受体表明平滑肌细胞不太可能通过结合C3b或Fc片段参与免疫复合物疾病的发病机制。

相似文献

1
Human umbilical cord vein smooth muscle cells lack receptors for C3b and the Fc portion of immunoglobulin G.人脐静脉平滑肌细胞缺乏C3b受体和免疫球蛋白G的Fc段受体。
Clin Immunol Immunopathol. 1984 Nov;33(2):282-6. doi: 10.1016/0090-1229(84)90082-5.
2
Modulation of neutrophil Fc and C3b receptors. Relationship with the phagocytic process and activation of the respiratory burst.中性粒细胞Fc和C3b受体的调节。与吞噬过程及呼吸爆发激活的关系。
Inflammation. 1983 Jun;7(2):155-68. doi: 10.1007/BF00917820.
3
Binding of immunoglobulin- and complement-coated erythrocytes to human neutrophil subpopulations.免疫球蛋白和补体包被的红细胞与人中性粒细胞亚群的结合。
Inflammation. 1981 Jun;5(2):103-14. doi: 10.1007/BF00914200.
4
Kinetic studies of neutrophil phagocytosis. V. studies on the co-operation between the Fc and C3b receptors.中性粒细胞吞噬作用的动力学研究。V. Fc和C3b受体之间协同作用的研究。
Immunology. 1982 Dec;47(4):687-94.
5
Endothelial cells of bovine pulmonary artery lack receptors for C3b and for the Fc portion of immunoglobulin G.牛肺动脉内皮细胞缺乏C3b受体和免疫球蛋白G的Fc段受体。
Science. 1980 May 16;208(4445):748-9. doi: 10.1126/science.7367890.
6
Fc and C3b receptor changes on mouse peritoneal leucocytes following stimulation with an extract of Ascaris suum.
Zentralbl Bakteriol Mikrobiol Hyg A. 1985 Aug;260(1):126-31. doi: 10.1016/s0176-6724(85)80108-5.
7
Distinct functions of surface receptors in the induction of neutrophil-mediated cytotoxicity.表面受体在诱导中性粒细胞介导的细胞毒性中的不同功能。
Ann Immunol (Paris). 1981 Jul-Aug;132D(1):3-14.
8
IgA-mediated inhibition of human leucocyte function by interference with Fc gamma and C3b receptors.通过干扰Fcγ和C3b受体,IgA介导对人白细胞功能的抑制。
Immunology. 1991 Sep;74(1):99-106.
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Factors influencing the endocytosis of immune complexes.影响免疫复合物内吞作用的因素。
Adv Nephrol Necker Hosp. 1984;13:341-67.
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Receptor associated defects of cultured monocytes in bronchial carcinoma.支气管癌中培养单核细胞的受体相关缺陷
Clin Exp Immunol. 1984 May;56(2):321-9.

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1
C1q binding to human vascular smooth muscle cells mediates immune complex deposition and superoxide generation.C1q与人类血管平滑肌细胞的结合介导免疫复合物沉积和超氧化物生成。
Inflammation. 1989 Oct;13(5):561-9. doi: 10.1007/BF00916762.