Ryan U S, Schultz D R, Del Vecchio P J, Ryan J W
Science. 1980 May 16;208(4445):748-9. doi: 10.1126/science.7367890.
Bovine pulmonary endothelial cells do not possess receptors for the 3b component of complement (C3b) or for the Fc portion of immunoglobulin G. The lack of these receptors may help explain the nonthrombogenic function of endothelial cells. Our findings rule out the possibility that endothelial cells participate in pulmonary immune complex disease through the binding of C3b or Fc fragments.
牛肺内皮细胞不具备补体3b成分(C3b)的受体,也不具备免疫球蛋白G的Fc部分的受体。这些受体的缺乏可能有助于解释内皮细胞的抗血栓形成功能。我们的研究结果排除了内皮细胞通过C3b或Fc片段的结合参与肺部免疫复合物疾病的可能性。