7种皮质类固醇的血管收缩和抗炎作用。

Vasoconstrictor and the anti-inflammatory effects of 7 corticosteroids.

作者信息

Crijns M B, Nater J P, van Oostveen F, van der Valk P G

出版信息

Contact Dermatitis. 1984 Aug;11(2):108-11. doi: 10.1111/j.1600-0536.1984.tb00936.x.

DOI:10.1111/j.1600-0536.1984.tb00936.x

Abstract

The vasoconstrictor effect of 7 proprietary corticosteroid creams was compared with their effect on patches of allergic contact dermatitis provoked by patch testing in 20 subjects. A parallel between the blanching effect on the normal skin and the anti-inflammatory effect on the eczematous skin was generally found. A modified patch test method using the Finn chamber technique is described, which (with certain restrictions) offers an opportunity of studying the anti-inflammatory effect of corticosteroids on allergic dermatitis under standard conditions.

摘要

将7种专利皮质类固醇乳膏的血管收缩作用与其对20名受试者进行斑贴试验引发的过敏性接触性皮炎斑块的作用进行了比较。通常发现正常皮肤的变白效应与湿疹皮肤的抗炎效应之间存在平行关系。描述了一种使用芬兰小室技术的改良斑贴试验方法，该方法（在一定限制条件下）提供了在标准条件下研究皮质类固醇对过敏性皮炎抗炎作用的机会。