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伴有假性视乳头水肿和脑缺血的高黏滞综合征

[Hyperviscosity syndrome with pseudopapilledema and cerebral ischemia].

作者信息

Gallasch G, Hartmann A

出版信息

Dtsch Med Wochenschr. 1984 Oct 26;109(43):1643-6. doi: 10.1055/s-2008-1069428.

Abstract

Papilloedema and fundal haemorrhages in a 46-year-old man were diagnosed to be due to polycythaemia and resultant abnormal blood viscosity. Viscosity was normalized by isovolemic haemodilution: papilloedema and fundal haemorrhages disappeared. Reduction in blood viscosity up to hyperfluidity increased mean regional cerebral blood flow, particularly in those areas of the brain in which initial blood flow was reduced. The effectiveness of isovolemic haemodilution was demonstrated in the patient by fluorescence angiography for the fundus, and by 133Xenon inhalation for cerebral blood flow.

摘要

一名46岁男性的视乳头水肿和眼底出血被诊断为是由红细胞增多症及由此导致的异常血液黏稠度引起的。通过等容血液稀释使血液黏稠度恢复正常:视乳头水肿和眼底出血消失。血液黏稠度降低至血液过度稀释状态可增加局部脑血流量平均值,尤其是在那些初始血流量减少的脑区。通过眼底荧光血管造影和氙133吸入法测定脑血流量,在该患者身上证实了等容血液稀释的有效性。

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