Sitbon G, Mialhe P
Horm Metab Res. 1978 Mar;10(2):117-23. doi: 10.1055/s-0028-1093456.
We have studied the pancreatic hormone-glucose feed-back mechanisms by infusing glucagon (G), insulin (I) and glucose into normal fasting geese. The controls received saline. Whilst a NaCl 9% infusion is devoid of effect, the pancreatic hormones, used at physiological doses, modify the plasma glucose level, glucagon being hyperglycaemic and insulin hypoglycaemic. In addition, a physiological increase in plasma glucose provokes a drop in plasma glucagon and a rise in plasma insulin, thus a marked decrease in the G/I ratio. The results show that the pancreatic hormone-glucose feed-back mechanisms are effective under physiological conditions.
我们通过向正常空腹鹅输注胰高血糖素（G）、胰岛素（I）和葡萄糖，研究了胰腺激素 - 葡萄糖反馈机制。对照组接受生理盐水。虽然输注9%的氯化钠没有效果，但生理剂量的胰腺激素会改变血浆葡萄糖水平，胰高血糖素使血糖升高，胰岛素使血糖降低。此外，血浆葡萄糖的生理性升高会导致血浆胰高血糖素下降和血浆胰岛素升高，从而使G/I比值显著降低。结果表明，胰腺激素 - 葡萄糖反馈机制在生理条件下是有效的。
