Lacko A G, Marks A D, Rutenberg H L, Soloff L A
Horm Metab Res. 1978 Mar;10(2):147-51. doi: 10.1055/s-0028-1093463.
The rate of serum cholesterol esterification was measured in twenty healthy subjects and compared to similar data obtained with seventeen hyperthyroid and ten hypothyroid subjects. No significant differences were noted in the rate of cholesterol esterification while differences in the fractional rates were highly significant (p less than 0.001); the hyperthyroid group being higher and the hypothyroid group lower than normal. There were no clear trends observed in the changes of the rate of cholesterol esterification upon therapy. However, the fractional rates always increased when hypothyroid patients became euthyroid and always decreased in hyperthyroid patients as the result of therapy.
测定了20名健康受试者的血清胆固醇酯化率，并与17名甲状腺功能亢进和10名甲状腺功能减退受试者的类似数据进行了比较。胆固醇酯化率未观察到显著差异，而分数率差异高度显著（p小于0.001）；甲状腺功能亢进组高于正常，甲状腺功能减退组低于正常。治疗后胆固醇酯化率的变化未观察到明显趋势。然而，甲状腺功能减退患者恢复正常甲状腺功能时分数率总是增加，而甲状腺功能亢进患者治疗后分数率总是降低。
