Yang Z Y, Hu H Y, Yan J H, Gu X Z
Int J Radiat Oncol Biol Phys. 1984 Nov;10(11):2067-76. doi: 10.1016/0360-3016(84)90204-9.
The range of doses which may lead to disappearance of local tumor after radiation treatment of esophageal carcinoma is extensive. Its possibility may reach 33% if the dose exceeds 5000 rad. However, the sensitivity of this cancer varies greatly in different patients. In clinical practice, the total dose should be decided according to the response of the tumor. Disappearance of local tumor signified better prognosis than otherwise. Radiation ulcer can be easily mistaken as local recurrence. Based upon clinical symptoms and X ray film, the possibility of misdiagnosing ulceration as local recurrence after radiotherapy of more than 6000 rad was as high as 29% (12/42) in our experience. The pathogenesis and management of radiation ulcer in the esophagus are discussed.
食管癌放射治疗后导致局部肿瘤消失的剂量范围很广。如果剂量超过5000拉德，其可能性可达33%。然而，这种癌症在不同患者中的敏感性差异很大。在临床实践中，总剂量应根据肿瘤的反应来决定。局部肿瘤消失意味着预后比其他情况更好。放射性溃疡很容易被误诊为局部复发。根据我们的经验，基于临床症状和X线片，在超过6000拉德放疗后将溃疡误诊为局部复发的可能性高达29%（12/42）。本文讨论了食管放射性溃疡的发病机制及处理方法。
