Yang Z Y, Gu X Z, Zhao S, Hong Z G, An H L, Hou F X, Xiang Q C, Guo B Z, Dong J P, Tian G D
Int J Radiat Oncol Biol Phys. 1983 Dec;9(12):1769-73. doi: 10.1016/0360-3016(83)90342-5.
One thousand one hundred and thirty-six patients surviving for more than five years after radiotherapy were studied. The important prognostic factors are: lesion less than 5 cm in length, lesion located in the upper-third segment and lesion that is radiosensitive. The radiation dose given to long term survivors varies greatly, i.e., 2700 to 9300 rad. Yet, for the sensitive type of lesion, doses lower than 5000 rad could also effect a cure. The delivery of an optimum dose determined by serial examinations during radiotherapy could improve the result of treatment. For local recurrent lesions, the value of a second course of radiation is extremely limited and surgery is the only means to offer a cure. For metastasis in the lymph nodes, radiation offers some hope of cure, although the long term outcome may not be satisfactory. For second primary cancer of the esophagus, aggressive radiation still gives encouraging results.
对1136例放疗后存活超过5年的患者进行了研究。重要的预后因素包括：病变长度小于5厘米、病变位于上段以及病变对放疗敏感。长期存活者所接受的辐射剂量差异很大，即2700至9300拉德。然而，对于敏感类型的病变，低于5000拉德的剂量也可能治愈。在放疗期间通过系列检查确定最佳剂量的给予可以改善治疗效果。对于局部复发病变，第二疗程放疗的价值极其有限，手术是唯一能治愈的手段。对于淋巴结转移，放疗提供了一些治愈的希望，尽管长期结果可能不尽人意。对于食管第二原发性癌，积极的放疗仍能给出令人鼓舞的结果。
