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肾上腺皮质结构和功能的性别差异。十六。成年雄性和雌性蒙古沙鼠(长爪沙鼠)完整肾上腺皮质的体视学和细胞核测量学研究

Sex differences in adrenocortical structure and function. XVI. Stereological and karyometric studies on the cortex of the suprarenal gland of intact adult male and female Mongolian gerbils (Meriones unguiculatus).

作者信息

Malendowicz L K

出版信息

J Anat. 1984 Oct;139 ( Pt 3)(Pt 3):525-33.

PMID:6490533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1165066/
Abstract

The histological structure of intact adult male and female Mongolian gerbil (Meriones unguiculatus) suprarenal cortex has been described, and quantitative stereological and karyometric studies were performed. The weight of the gland relative to body weight was higher in female than in male gerbils, but the volume of the gland was similar in both sexes. The relative volume of the zona reticularis was higher in the female, while no sex difference was observed in the absolute volume of all suprarenal components (expressed in mm3). In all cortical zones, average cell volume was higher in the female; the nuclear volume of the zona glomerulosa and zona reticularis were also higher in the female. In the zona fasciculata, some large cells with large nuclei (greater than 210 micrometers 3) were observed. These are probably polyploid cells and have not been described in other species. The suprarenal cortex of the male gerbil contained more parenchymal cells than that of the female, the difference being dependent upon variation in the number of cells in the zona fasciculata and zona reticularis. Despite these structural differences, gland homogenates from male and female animals secreted similar amounts of cortisol and the plasma levels in the two sexes were the same.

摘要

已描述了成年雄性和雌性蒙古沙鼠(Meriones unguiculatus)完整肾上腺皮质的组织学结构,并进行了定量立体学和核测量学研究。相对于体重而言,雌性沙鼠肾上腺的重量高于雄性,但肾上腺的体积在两性中相似。雌性网状带的相对体积较高,而所有肾上腺成分的绝对体积(以立方毫米表示)未观察到性别差异。在所有皮质区,雌性的平均细胞体积更大;球状带和网状带的核体积在雌性中也更大。在束状带中,观察到一些具有大核(大于210立方微米)的大细胞。这些可能是多倍体细胞,在其他物种中尚未有描述。雄性沙鼠的肾上腺皮质比雌性含有更多的实质细胞,差异取决于束状带和网状带中细胞数量的变化。尽管存在这些结构差异,但雄性和雌性动物的腺体匀浆分泌的皮质醇量相似,两性的血浆水平相同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2239/1165066/0a09e48b4421/janat00199-0130-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2239/1165066/0a09e48b4421/janat00199-0130-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2239/1165066/0a09e48b4421/janat00199-0130-a.jpg

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本文引用的文献

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Endocrinology. 1958 Sep;63(3):349-58. doi: 10.1210/endo-63-3-349.
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Effects of rearing environment on adrenal weights, sexual development, and behavior in gerbils: an examination of Richter's domestication hypothesis.饲养环境对沙鼠肾上腺重量、性发育及行为的影响:对里希特驯化假说的检验
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Effect of estradiol-17 alpha and diethylstilbestrol on adrenal cortex and anterior pituitary gland of the Mongolian gerbil.
17α-雌二醇和己烯雌酚对长爪沙鼠肾上腺皮质和垂体前叶的影响。
Tissue Cell. 1980;12(1):117-23. doi: 10.1016/0040-8166(80)90055-5.
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Environment influence on development, behavior, and endocrine morphology of gerbils.环境对沙鼠发育、行为及内分泌形态的影响。
Physiol Behav. 1981 Nov;27(5):761-5. doi: 10.1016/0031-9384(81)90039-1.
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Z Mikrosk Anat Forsch. 1982;96(1):91-102.
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