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Toxoplasma antigen isolated by affinity chromatography with monoclonal antibody protects mice against lethal infection with Toxoplasma gondii.

作者信息

Sharma S D, Araujo F G, Remington J S

出版信息

J Immunol. 1984 Dec;133(6):2818-20.

PMID:6491277
Abstract
摘要

相似文献

1
Toxoplasma antigen isolated by affinity chromatography with monoclonal antibody protects mice against lethal infection with Toxoplasma gondii.通过与单克隆抗体进行亲和层析分离得到的弓形虫抗原可保护小鼠免受刚地弓形虫的致死性感染。
J Immunol. 1984 Dec;133(6):2818-20.
2
An unexpected response to vaccination with a purified major membrane tachyzoite antigen (P30) of Toxoplasma gondii.对刚地弓形虫纯化主要膜速殖子抗原(P30)疫苗接种的意外反应。
J Immunol. 1985 May;134(5):3426-31.
3
Evaluation of immunization with tachyzoite excreted-secreted proteins in a novel susceptible mouse model (A/Sn) for Toxoplasma gondii.在一种新型的对刚地弓形虫易感的小鼠模型(A/Sn)中对速殖子排泄-分泌蛋白免疫接种的评估。
Exp Parasitol. 2008 Nov;120(3):227-34. doi: 10.1016/j.exppara.2008.07.015. Epub 2008 Jul 31.
4
Antibodies to Toxoplasma gondii major surface protein (SAG-1, P30) inhibit infection of host cells and are produced in murine intestine after peroral infection.抗刚地弓形虫主要表面蛋白(SAG-1,P30)的抗体可抑制宿主细胞感染,且在经口感染后在小鼠肠道中产生。
J Immunol. 1993 May 1;150(9):3951-64.
5
[Experimental animal studies for the detection of circulating Toxoplasma antigens].用于检测循环中弓形虫抗原的实验动物研究
Angew Parasitol. 1991 May;32(2):93-8.
6
Induction of tolerance to an intracellular protozoan (Toxoplasma gondii) by passively administered antibody.通过被动给予抗体诱导对细胞内原生动物(刚地弓形虫)的耐受性。
J Immunol. 1974 Nov;113(5):1424-8.
7
Monoclonal antibodies against nucleoside triphosphate hydrolase-II can reduce the replication of Toxoplasma gondii.抗三磷酸核苷水解酶-II的单克隆抗体可减少刚地弓形虫的复制。
Parasitol Int. 2010 Jun;59(2):141-6. doi: 10.1016/j.parint.2009.12.007. Epub 2010 Jan 6.
8
IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice.白细胞介素-15增强小鼠体内CD8 + T细胞介导的抗弓形虫感染免疫反应。
J Immunol. 1996 Sep 1;157(5):2103-8.
9
Toxoplasma gondii: identification and characterization of a cyst molecule.刚地弓形虫:一种包囊分子的鉴定与特性分析
Exp Parasitol. 1995 Mar;80(2):228-33. doi: 10.1006/expr.1995.1028.
10
Identification of stage-specific sporozoite antigens of Toxoplasma gondii by monoclonal antibodies.用单克隆抗体鉴定刚地弓形虫阶段特异性子孢子抗原
J Immunol. 1984 Jan;132(1):443-9.

引用本文的文献

1
Toxoplasma gondii-Derived Synthetic Peptides Containing B- and T-Cell Epitopes from GRA2 Protein Are Able to Enhance Mice Survival in a Model of Experimental Toxoplasmosis.含有来自GRA2蛋白的B细胞和T细胞表位的弓形虫衍生合成肽能够提高实验性弓形虫病模型中小鼠的存活率。
Front Cell Infect Microbiol. 2016 Jun 1;6:59. doi: 10.3389/fcimb.2016.00059. eCollection 2016.
2
Comparison of protective immune responses to apicomplexan parasites.针对顶复门寄生虫的保护性免疫反应比较。
J Parasitol Res. 2012;2012:852591. doi: 10.1155/2012/852591. Epub 2011 Aug 18.
3
Toxoplasma gondii: expression and characterization of a recombinant protein containing SAG1 and GRA2 in Pichia pastoris.
刚地弓形虫:在毕赤酵母中表达及鉴定含SAG1和GRA2的重组蛋白
Parasitol Res. 2007 Mar;100(4):829-35. doi: 10.1007/s00436-006-0341-6. Epub 2006 Oct 21.
4
Effects of specific monoclonal antibodies to dense granular proteins on the invasion of Toxoplasma gondii in vitro and in vivo.针对致密颗粒蛋白的特异性单克隆抗体对刚地弓形虫体内外侵袭的影响
Korean J Parasitol. 2001 Sep;39(3):233-40. doi: 10.3347/kjp.2001.39.3.233.
5
B cells are essential for vaccination-induced resistance to virulent Toxoplasma gondii.B细胞对于疫苗接种诱导的对强毒力刚地弓形虫的抵抗力至关重要。
Infect Immun. 2000 Mar;68(3):1026-33. doi: 10.1128/IAI.68.3.1026-1033.2000.
6
Targeted disruption of the GRA2 locus in Toxoplasma gondii decreases acute virulence in mice.对刚地弓形虫中GRA2基因座的靶向破坏会降低小鼠的急性毒力。
Infect Immun. 1998 Sep;66(9):4176-82. doi: 10.1128/IAI.66.9.4176-4182.1998.
7
Protective immunity in toxoplasmosis: correlation between antibody response, brain cyst formation, T-cell activation, and survival in normal and B-cell-deficient mice bearing the H-2k haplotype.弓形虫病中的保护性免疫:具有H-2k单倍型的正常和B细胞缺陷小鼠的抗体反应、脑囊肿形成、T细胞活化与生存之间的相关性。
Infect Immun. 1987 Apr;55(4):990-4. doi: 10.1128/iai.55.4.990-994.1987.
8
Prevention of peroral and congenital acquisition of Toxoplasma gondii by antibody and activated macrophages.通过抗体和活化巨噬细胞预防经口和先天性感染刚地弓形虫。
Infect Immun. 1988 Jan;56(1):83-7. doi: 10.1128/iai.56.1.83-87.1988.
9
Ultrastructural localization of an intracellular Toxoplasma protein that induces protection in mice.一种可诱导小鼠产生保护作用的细胞内弓形虫蛋白的超微结构定位
Infect Immun. 1987 Sep;55(9):2137-41. doi: 10.1128/iai.55.9.2137-2141.1987.
10
Treatment of toxoplasmic encephalitis in mice with recombinant gamma interferon.用重组γ干扰素治疗小鼠弓形虫性脑炎。
Infect Immun. 1990 Sep;58(9):3050-5. doi: 10.1128/iai.58.9.3050-3055.1990.