Killewich L A, Martin R, Cramer M, Beach K W, Strandness D E
J Vasc Surg. 1984 Jul;1(4):507-11.
Patients with chronic iliofemoral venous obstruction may develop severe thigh pain and a sensation of tightness with vigorous exercise (venous claudication). The discomfort requires 15 to 20 minutes to subside. In the seven patients studied the venous capacitance (VC) and venous outflow (VO) are lower than those of the unaffected limb even at rest. With exercise to the point of pain, the VO was unchanged but the VC decreased even further. The problem appears to rest with the venous collaterals, which have a high and fixed resistance. Because of this high outflow resistance, venous volume increases to near maximum during exercise. With this rise in venous volume, the amount the VC can increase during the period immediately following exercise is further reduced.
患有慢性髂股静脉阻塞的患者在剧烈运动时可能会出现严重的大腿疼痛和紧绷感（静脉性跛行）。这种不适需要15至20分钟才能缓解。在研究的7名患者中，即使在休息时，静脉容量（VC）和静脉流出量（VO）也低于未受影响的肢体。运动至疼痛程度时，VO不变，但VC进一步降低。问题似乎在于静脉侧支，其具有高且固定的阻力。由于这种高流出阻力，运动期间静脉容量增加至接近最大值。随着静脉容量的这种增加，运动后紧接着的时间段内VC能够增加的量会进一步减少。
