Imperato J P, Weichselbaum R R, Ervin T J
J Surg Oncol. 1984 Nov;27(3):163-7. doi: 10.1002/jso.2930270307.
Twenty-nine patients treated with postoperative radiotherapy for malignant tumors of the parotid gland were reviewed at the Joint Center for Radiation Therapy. Most patients were treated between 5,000 and 6,500 rad. All were treated because of microscopic residual disease, extra capsular extension, or tumor close to the facial nerve. The overall results showed one in-field failure, two marginal recurrences, and eight patients failed distantly. Poor prognostic factors included high-grade, extracapsular extension, and nodal involvement. We conclude that patients with malignant tumors of the parotid should be treated with postoperative radiation therapy if any of the bad prognostic signs are present. This may enable the surgeon to spare the facial nerve and obtain local control results equal to or better than more radical surgical procedures.
在放射治疗联合中心对29例接受腮腺恶性肿瘤术后放疗的患者进行了回顾性研究。大多数患者接受了5000至6500拉德的放疗。所有患者均因显微镜下残留病灶、包膜外扩展或肿瘤靠近面神经而接受治疗。总体结果显示，有1例野内复发、2例边缘复发，8例远处复发。不良预后因素包括高级别、包膜外扩展和淋巴结受累。我们得出结论，如果存在任何不良预后迹象，腮腺恶性肿瘤患者应接受术后放射治疗。这可能使外科医生能够保留面神经，并获得与更根治性手术相当或更好的局部控制效果。
