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一种牛呼吸道合胞病毒疫苗的田间试验。

Field trials of a bovine respiratory syncytial virus vaccine.

作者信息

Bohlender R E

出版信息

Mod Vet Pract. 1984 Aug;65(8):606-9.

PMID:6493205
Abstract

A vaccine against bovine respiratory syncytial virus (BRSV: Norden), a cause of pulmonary edema-emphysema and pneumonia in calves, was evaluated in field trials on western Nebraska beef calves at branding, preweaning, weaning and postweaning. Of calves with undifferentiated respiratory infection at weaning, 20.9% of 2-dose vaccinates (169/810) and 27.5% of 1-dose vaccinates (230/837) required treatment, vs 48.2% of unvaccinated controls (397/823). At postweaning, 2.4% of 2-dose vaccinates (13/548) and 4.7% of 1-dose vaccinates (28/598) required treatment, vs 20.5% of controls (181/885). Studies in the 2 subsequent years revealed 11.3% of calves vaccinated at preweaning (263/2312) required treatment, vs 24.4% of controls (387/1587). Average costs from respiratory disease in 5 herds ranged from $12.83/head to $46.99/head before BRSV vaccination and 4/head to 54/head after vaccination.

摘要

一种针对牛呼吸道合胞病毒(BRSV:诺登株)的疫苗在西内布拉斯加州肉牛犊的田间试验中进行了评估,该病毒是犊牛肺水肿 - 肺气肿和肺炎的病因,试验分别在烙印期、断奶前、断奶时和断奶后进行。在断奶时患有未分化呼吸道感染的犊牛中,两剂接种疫苗的犊牛中有20.9%(169/810)和一剂接种疫苗的犊牛中有27.5%(230/837)需要治疗,而未接种疫苗的对照组中有48.2%(397/823)需要治疗。在断奶后,两剂接种疫苗的犊牛中有2.4%(13/548)和一剂接种疫苗的犊牛中有4.7%(28/598)需要治疗,而对照组中有20.5%(181/885)需要治疗。随后两年的研究显示,断奶前接种疫苗的犊牛中有11.3%(263/2312)需要治疗,而对照组中有24.4%(387/1587)需要治疗。在5个牛群中,BRSV疫苗接种前呼吸道疾病的平均成本为每头12.83美元至46.99美元,接种后为每头4美元至54美元。

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引用本文的文献

1
Five field trials on the efficacy of a bovine respiratory syncytial virus vaccine.一项牛呼吸道合胞体病毒疫苗效力的五项田间试验。
Can Vet J. 1990 Feb;31(2):93-100.