Appel G, Heckert H P
Dtsch Tierarztl Wochenschr. 1989 Apr;96(4):226-8.
It is reported on atypical interstitial pneumonia (AIP) in 16 mostly Holstein-Frisian calves and feeders from 13 different farms in Schleswig-Holstein in association with an infection by the respiratory syncytial virus (BRSV). All animals were submitted with identical clinical histories. Macroscopically the lung lesions were characterized by alveolar and interstitial edema and emphysema. Microscopically there was a diffuse interstitial pneumonia with formation of hyaline membranes and multinucleated giant cells. From the investigation material of the 16 animals BRSV was confirmed by direct immunofluorescence with monoclonal antibodies in 4 animals from 4 different farms.
据报道,石勒苏益格-荷尔斯泰因州13个不同农场的16头主要为荷斯坦-弗里生犊牛和育肥牛出现非典型间质性肺炎(AIP),与呼吸道合胞病毒(BRSV)感染有关。所有动物的临床病史相同。宏观上,肺部病变的特征为肺泡和间质水肿以及肺气肿。微观上,存在弥漫性间质性肺炎,伴有透明膜和多核巨细胞形成。在16只动物的调查材料中,通过单克隆抗体直接免疫荧光法在来自4个不同农场的4只动物中确诊了BRSV。