Katznelson D, Ben-Yishay M
Isr J Med Sci. 1978 Feb;14(2):204-11.
A total of 140 cases of cystic fibrosis in 110 families was identified in Israel during the years 1946--75, and there was reason to suspect inadequate ascertainment. Cystic fibrosis is frequent among the Ashkenazic and Arab populations with an incidence approximating that for Caucasians of European ancestry (1:1,800 to 1:4,000 live births). It is about half as frequent in the Sephardim, rare in the Iraqi or Yemenite Jews and perhaps absent in Iranian Jews. The clinical picture of cystic fibrosis in Israel in all the ethnic groups was found to be the same as elsewhere in the world. In-depth.interviews of 50 families were conducted to assess their understanding of the genetics of the disease and their attitude toward family planning.
1946年至1975年间，以色列共确诊了110个家庭中的140例囊性纤维化病例，有理由怀疑确诊不充分。囊性纤维化在阿什肯纳兹人和阿拉伯人群中很常见，发病率与欧洲血统的白种人相近（每1800至4000例活产中有1例）。在西班牙系犹太人中发病率约为前者的一半，在伊拉克或也门犹太人中很少见，在伊朗犹太人中可能不存在。研究发现，以色列所有种族群体中囊性纤维化的临床表现与世界其他地方相同。对50个家庭进行了深入访谈，以评估他们对该疾病遗传学的理解以及他们对计划生育的态度。
