Rodríguez E, Castella J, Puzo C, de Andrés L, Cornudella R
Respiration. 1984;46(3):323-7. doi: 10.1159/000194706.
During 3 years, a prospective study was undertaken to investigate the frequency of lung cancer (LC) in patients with a tracheostomy after laryngectomy for neoplasm of the larynx (LxC). The protocol required a thorax radiography (RX) and a bronchofiberscopy (BF) every 6 months in each patient. Of the 286 cases studied, a diagnosis of LC was made in 36 (12.5%). In 6 of these 36 patients, there were no symptoms suggestive of LC and the RX was normal, and the diagnosis of LC was made only by systematic BF. A surgical treatment of LC was possible in only 7 cases. These results suggest that there is a high frequency of LC in patients with tracheostomy due to LxC, and also that it would be better to restrict the follow-up with systematic BF to those patients suitable for thoracotomy.
在3年期间，进行了一项前瞻性研究，以调查喉肿瘤喉切除术（LxC）后气管切开术患者中肺癌（LC）的发生频率。该方案要求对每位患者每6个月进行一次胸部X线摄影（RX）和纤维支气管镜检查（BF）。在研究的286例病例中，36例（12.5%）被诊断为LC。在这36例患者中的6例中，没有提示LC的症状，RX正常，仅通过系统性BF诊断为LC。仅7例患者可行LC手术治疗。这些结果表明，LxC导致气管切开术的患者中LC发生率较高，并且还表明，将系统性BF随访限制在适合开胸手术的患者中可能更好。
