Hoyes A D, Barber P
J Anat. 1978 May;126(Pt 1):203-7.
The cross sectional appearances of the lumen of rat ureter were compared in specimens fixed by perfusion and by immersion and processed for electron microscopy. After efficient perfusion fixation in untreated animals, and in animals previously injected with 6-hydroxydopamine, there was substantial dilatation of the ureter, and the lumen was approximately circular in section. In inadequately perfused and immersion-fixed material the lumen was usually narrowed, and was either slit-like or stellate in appearance. Ultrastructural examination indicated that closure of the lumen was accompanied by the development in the cells of the muscle coat of the features usually associated with contraction, and the possibility that the appearance of the ureter in well perfused specimens approximated to its state in vivo was discussed.
对通过灌注固定和浸入固定并进行电子显微镜处理的大鼠输尿管管腔横断面外观进行了比较。在未经处理的动物以及先前注射过6-羟基多巴胺的动物中进行有效灌注固定后，输尿管出现明显扩张，管腔横断面近似圆形。在灌注不充分和浸入固定的材料中，管腔通常变窄，外观呈裂隙状或星状。超微结构检查表明，管腔闭合伴随着肌层细胞中通常与收缩相关特征的出现，并且讨论了灌注良好的标本中输尿管外观接近其体内状态的可能性。
