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Bioconversion and biosynthesis of 16-membered macrolide antibiotic, tylosin, using enzyme inhibitor: cerulenin.

作者信息

Omura S, Kitao C, Miyazawa J, Imai H, Takeshima H

出版信息

J Antibiot (Tokyo). 1978 Mar;31(3):254-6. doi: 10.7164/antibiotics.31.254.

Abstract
摘要

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Bioconversion and biosynthesis of 16-membered macrolide antibiotic, tylosin, using enzyme inhibitor: cerulenin.
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引用本文的文献

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Properties of Streptomyces fradiae mutants blocked in biosynthesis of the macrolide antibiotic tylosin.
Antimicrob Agents Chemother. 1981 Aug;20(2):214-25. doi: 10.1128/AAC.20.2.214.
2
Incorporation of amino acid-derived carbon into tylactone by Streptomyces fradiae GS14.
Antimicrob Agents Chemother. 1984 Feb;25(2):216-20. doi: 10.1128/AAC.25.2.216.
3
Enzymes of secondary metabolism and the biosynthesis of macrolide antibiotics.
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