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Chimeramycins: new macrolide antibiotics produced by hybrid biosynthesis.

作者信息

Omura S, Sadakane N, Tanaka Y, Matsubara H

出版信息

J Antibiot (Tokyo). 1983 Jul;36(7):927-30. doi: 10.7164/antibiotics.36.927.

DOI:10.7164/antibiotics.36.927

PMID:6860432

Abstract

摘要

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Chimeramycins: new macrolide antibiotics produced by hybrid biosynthesis.

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Chimeramycins: new macrolide antibiotics produced by hybrid biosynthesis.

作者信息

Omura S, Sadakane N, Tanaka Y, Matsubara H

出版信息

J Antibiot (Tokyo). 1983 Jul;36(7):927-30. doi: 10.7164/antibiotics.36.927.

DOI:10.7164/antibiotics.36.927

PMID:6860432

Abstract

摘要

相似文献

Chimeramycins: new macrolide antibiotics produced by hybrid biosynthesis.

J Antibiot (Tokyo). 1983 Jul;36(7):927-30. doi: 10.7164/antibiotics.36.927.

Hybrid biosynthesis of a new macrolide antibiotic by a daunomycin-producing microorganism.

J Antibiot (Tokyo). 1983 Jul;36(7):921-2. doi: 10.7164/antibiotics.36.921.

New tylosin analogs produced by mutants of Streptomyces fradiae.

J Antibiot (Tokyo). 1987 Aug;40(8):1123-30. doi: 10.7164/antibiotics.40.1123.

Studies on the biosynthesis of 16-membered macrolide antibiotics using carbon-13 nuclear magnetic resonance spectroscopy.

Biochemistry. 1977 Jun 28;16(13):2860-6. doi: 10.1021/bi00632a009.

Terminal stages in the biosynthesis of tylosin.

Antimicrob Agents Chemother. 1977 Mar;11(3):455-61. doi: 10.1128/AAC.11.3.455.

Hybrid biosynthesis of derivatives of protylonolide and M-4365 by macrolide-producing microorganisms.

J Antibiot (Tokyo). 1982 Jun;35(6):680-7. doi: 10.7164/antibiotics.35.680.

Preparation and evaluation of 3,4''-ester derivatives of 16-membered macrolide antibiotics related to tylosin.

J Antibiot (Tokyo). 1986 Dec;39(12):1724-35. doi: 10.7164/antibiotics.39.1724.

Bioconversion and biosynthesis of 16-membered macrolide antibiotic, tylosin, using enzyme inhibitor: cerulenin.

J Antibiot (Tokyo). 1978 Mar;31(3):254-6. doi: 10.7164/antibiotics.31.254.

Bioconversion and biosynthesis of 16-membered macrolide antibiotics. XV. Final steps in the biosynthesis of leucomycins.

J Antibiot (Tokyo). 1979 Oct;32(10):1055-7. doi: 10.7164/antibiotics.32.1055.

Ammonium ion suppresses the biosynthesis of tylosin aglycone by interference with valine catabolism in Streptomyces fradiae.

J Antibiot (Tokyo). 1983 Dec;36(12):1792-4. doi: 10.7164/antibiotics.36.1792.

引用本文的文献

A comprehensive review of glycosylated bacterial natural products.

Chem Soc Rev. 2015 Nov 7;44(21):7591-697. doi: 10.1039/c4cs00426d.

Post-PKS tailoring steps of the spiramycin macrolactone ring in Streptomyces ambofaciens.

Antimicrob Agents Chemother. 2013 Aug;57(8):3836-42. doi: 10.1128/AAC.00512-13. Epub 2013 May 28.

Combined chemical and biosynthetic route to access a new apoptolidin congener.

Org Lett. 2009 Jul 16;11(14):3032-4. doi: 10.1021/ol901045v.

Philosophy of new drug discovery.

Microbiol Rev. 1986 Sep;50(3):259-79. doi: 10.1128/mr.50.3.259-279.1986.

Production of new hybrid antibiotics, mederrhodins A and B, by a genetically engineered strain.

Antimicrob Agents Chemother. 1986 Jan;29(1):13-9. doi: 10.1128/AAC.29.1.13.

Cloning of spiramycin biosynthetic genes and their use in constructing Streptomyces ambofaciens mutants defective in spiramycin biosynthesis.

J Bacteriol. 1990 Jul;172(7):3790-8. doi: 10.1128/jb.172.7.3790-3798.1990.