Khokhlov A N, Chirkova E Iu, Nadzharian T L
Tsitologiia. 1984 Aug;26(8):965-8.
A gradual accumulation of the alkali-labile sites in DNA of cultured Chinese hamster cells during "stationary phase ageing" was shown by ultracentrifugation in alkaline sucrose gradients. A possibility is discussed of using the stationary phase mammalian cell cultures as a model for studies of ageing mechanisms.
通过碱性蔗糖梯度超速离心法表明,在“静止期老化”过程中,培养的中国仓鼠细胞DNA中的碱不稳定位点会逐渐积累。文中讨论了将静止期哺乳动物细胞培养用作衰老机制研究模型的可能性。