[The effect of 3',5'-AMP-dependent protein kinase on the release of cathepsin B from lysosomes of rat skeletal muscles and heart under exertion].

Single prolonged physical exercises are found to lower the total and bound activity of cathepsin D in the lysosome fraction and to enhance the nonsedimentary activity of the enzyme the dissolved fraction of the skeletal muscles and heart lysosomes. Systematic physical exercises make higher the ability of 3':5'-AMP-dependent protein kinases to regulate the yield of cathepsin D from lysosomes.