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[大肠恶性肿瘤中的类固醇激素受体]

[Steroid hormone receptors in malignant tumors of the large intestine].

作者信息

Korotkova T V, Bassalyk L S, Knysh V I, Prorokov V V

出版信息

Vopr Onkol. 1984;30(9):64-8.

PMID:6495697
Abstract

Receptors of steroid hormones (estrogens, androgens, progesterone and glucocorticoids) were studied in 60 patients with stage II-III primary cancer of the large bowel. In 58%, tumors were receptor-positive, with receptors of estrogens and glucocorticoids being the most frequent. No correlation between the frequency of receptor identification and the patients' sex, age, tumor's site or stage was established. Since it is suggested that large bowel cancer may be hormone-sensitive, it makes the case for development of new methods of prevention and treatment of the disease.

摘要

对60例Ⅱ - Ⅲ期原发性大肠癌患者的类固醇激素(雌激素、雄激素、孕酮和糖皮质激素)受体进行了研究。58% 的肿瘤受体呈阳性,其中雌激素和糖皮质激素受体最为常见。未发现受体识别频率与患者性别、年龄、肿瘤部位或分期之间存在相关性。鉴于提示大肠癌可能对激素敏感,这为开发该疾病的新预防和治疗方法提供了依据。

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