[Cytoplasmic steroid hormone receptors in primary breast tumors].

Receptors of steroid hormones (estrogens, progesterone and glucocorticoids) were studied in 148 patients with primary tumors of the mammary gland at different stages. All three types of receptors were found in 40% of patients. Receptor levels were compared versus menstrual status, histological pattern of tumor and preliminary chemo-hormonotherapy. It was established that estrogen and progesterone levels depend on menstrual status. No significant correlation was found between the degree of tumor cell differentiation and level of estrogen receptors. A retrospective assessment of estrogen receptor level and chemo-hormonotherapy results in 74 premenopausal patients with stage II tumor is given.