Bassalyk L S, Murav'eva N I, Smirnova K D, Kuz'mina Z V, Vishniakova V V
Vopr Onkol. 1982;28(4):6-10.
Receptors of steroid hormones (estrogens, progesterone and glucocorticoids) were studied in 148 patients with primary tumors of the mammary gland at different stages. All three types of receptors were found in 40% of patients. Receptor levels were compared versus menstrual status, histological pattern of tumor and preliminary chemo-hormonotherapy. It was established that estrogen and progesterone levels depend on menstrual status. No significant correlation was found between the degree of tumor cell differentiation and level of estrogen receptors. A retrospective assessment of estrogen receptor level and chemo-hormonotherapy results in 74 premenopausal patients with stage II tumor is given.
对148例处于不同阶段的原发性乳腺癌患者的类固醇激素（雌激素、孕激素和糖皮质激素）受体进行了研究。40%的患者检测到所有三种类型的受体。将受体水平与月经状态、肿瘤组织学模式和初步化疗-激素治疗进行了比较。结果表明，雌激素和孕激素水平取决于月经状态。未发现肿瘤细胞分化程度与雌激素受体水平之间存在显著相关性。对74例II期肿瘤的绝经前患者的雌激素受体水平和化疗-激素治疗结果进行了回顾性评估。
