Katenkamp D, Perevoshchikov A G, Raikhlin N T
Vopr Onkol. 1984;30(9):69-75.
An ultrastructural examination of 18 colonic carcinomas detected myofibroblasts in 13 tumors. An inverse correlation was established between the level of myofibroblasts and the number of inflammatory cells. A multi-layered vascular basal membrane was found in the capillary vessels of 5 carcinomas. Myofibroblasts were invariably accompanied by altered smooth muscle cells corresponding to pericytes with smooth muscle traits. The findings suggest that myofibroblasts may develop from fibroblasts, smooth muscle cells of the intestinal wall and cells of vascular structures.
对18例结肠癌进行的超微结构检查发现，13例肿瘤中有肌成纤维细胞。肌成纤维细胞水平与炎症细胞数量之间呈负相关。在5例癌的毛细血管中发现了多层血管基底膜。肌成纤维细胞总是伴有与具有平滑肌特征的周细胞相对应的平滑肌细胞改变。这些发现表明，肌成纤维细胞可能由成纤维细胞、肠壁平滑肌细胞和血管结构细胞发育而来。
