Jaszczak P, Sejrsen P
Acta Anaesthesiol Scand. 1984 Oct;28(5):482-9. doi: 10.1111/j.1399-6576.1984.tb02103.x.
133Xe washout measurements were used to determine cutaneous and subcutaneous blood flow beneath a specially designed double-thermostat tc-PO2 electrode. The skin blood flow was determined using thermal methods based on reduced heat dissipation during blood flow cessation. A total of 20 measurements were performed on two healthy volunteers, using the volar side of the right forearm as the experimental area. Cutaneous as well as subcutaneous blood flow increased with increasing electrode temperature. The cutaneous blood flow increased from 12.3 +/- 1.3 ml (100 g)-1 X min-1 (37 degrees C) to 49.1 +/- 5.4 ml (100 g)-1 X min-1 (45 degrees C) and the subcutaneous values from 20.9 +/- 0.2 ml (100 g)-1 X min-1 to 57.3 +/- 0.5 ml (100 g)-1 X min-1. Preheating of the measuring area or injection of papaverine as blood flow accelerator did not increase the maximum blood flow values. A considerable inter-individual difference between cutaneous and subcutaneous blood flow was observed, but in spite of that a good overall correlation between the 133Xe washout measurements and the two thermal flow measurements was found (r = 0.932 and 0.945, respectively). It is concluded that in some cases, but not always, measurements of tc-PO2 at electrode temperatures of 45 degrees C take place on a maximally perfused skin and that it is possible to determine skin blood flow by means of determinations of the heat dissipated from the tc-PO2 electrode to the underlying skin.
采用¹³³Xe洗脱测量法测定特制双恒温tc-PO₂电极下方的皮肤和皮下血流。基于血流停止时散热减少，采用热学方法测定皮肤血流。以两名健康志愿者右前臂掌侧作为实验区域，共进行了20次测量。皮肤和皮下血流均随电极温度升高而增加。皮肤血流从12.3±1.3 ml(100 g)⁻¹·min⁻¹(37℃)增至49.1±5.4 ml(100 g)⁻¹·min⁻¹(45℃)，皮下血流值从20.9±0.2 ml(100 g)⁻¹·min⁻¹增至57.3±0.5 ml(100 g)⁻¹·min⁻¹。测量区域预热或注射罂粟碱作为血流促进剂并未增加最大血流值。观察到皮肤和皮下血流存在显著个体差异，但尽管如此，¹³³Xe洗脱测量与两种热学血流测量之间仍具有良好的总体相关性（分别为r = 0.932和0.945）。得出结论，在某些情况下（但并非总是如此），在电极温度为45℃时进行tc-PO₂测量是在灌注最大化的皮肤上进行的，并且可以通过测定从tc-PO₂电极散发到其下方皮肤的热量来确定皮肤血流。
