Magnusson B, Hallberg L, Rossander L, Swolin B
Acta Med Scand. 1984;216(2):149-55.
Several reports have suggested that iron deficiency might explain "sports anemia" especially in long distance runners. The present study was made to further study the iron metabolism in runners as the proposed cause of "sports anemia" is abstruse considering the good iron nutrition in these athletes. Based on a screening of 43 elite male runners, using bone marrow hemosiderin, serum ferritin and transferrin saturation, two groups of subjects were selected for a very extensive study on iron metabolism. In group 1 (n = 5) iron depletion was suggested in at least one of the screening studies. In group 2 (n = 7) at least one test strongly indicated good iron repletion. This experimental design was chosen to obtain two groups with similar body composition and exercise load but different iron metabolism. The studies comprised determinations of red cell and plasma volumes, plasma iron turnover and red cell incorporation of radioiron, red cell indices, plasma iron and transferrin, red cell protoporphyrin, serum ferritin, serum haptoglobin, urinary iron losses, iron absorption, bone marrow hemosiderin, dietary intake of energy and nutrients and a Desferal test. Pooling the results together it was obvious that none of the subjects were truly iron-deficient. A few occasional findings suggesting low iron stores cannot be satisfactorily explained and indicate that further studies are needed.
几份报告表明，缺铁可能是“运动性贫血”的原因，尤其在长跑运动员中。鉴于这些运动员良好的铁营养状况，“运动性贫血”的假定原因难以理解，因此开展了本研究以进一步探究跑步运动员的铁代谢情况。基于对43名精英男性跑步运动员的筛查，通过骨髓含铁血黄素、血清铁蛋白和转铁蛋白饱和度，选取了两组受试者进行一项关于铁代谢的广泛研究。在第1组（n = 5）中，至少一项筛查研究提示存在铁耗竭。在第2组（n = 7）中，至少一项检测强烈表明铁储备良好。选择这种实验设计是为了获得两组身体组成和运动负荷相似但铁代谢不同的受试者。研究包括测定红细胞和血浆容量、血浆铁周转率和放射性铁在红细胞中的掺入、红细胞指数、血浆铁和转铁蛋白、红细胞原卟啉、血清铁蛋白、血清触珠蛋白、尿铁流失、铁吸收、骨髓含铁血黄素、能量和营养素的饮食摄入以及去铁胺试验。综合各项结果显而易见，没有受试者真正缺铁。一些偶尔出现的提示铁储备低的结果无法得到满意解释，这表明需要进一步研究。
