Birgegård G, Carlsson M, Sandhagen B, Mannting F
Acta Med Scand. 1984;216(2):165-9. doi: 10.1111/j.0954-6820.1984.tb03788.x.
The relation between whole blood viscosity and iron status was studied in 11 patients with polycythemia vera (PV) who were treated with venesection without iron supplementation. Six were already iron deficient at the start of the study, five were followed from normal iron status to deficiency. Iron status was investigated with serum ferritin, erythrocyte protoporphyrin, mean cell volume and mean cell hemoglobin. There was no correlation between whole blood viscosity at a fixed erythrocyte volume fraction of 44% and any of these variables. The mean whole blood viscosity during iron deficiency and during normal iron state did not differ. Even after several months of iron deficiency there was no increase in whole blood viscosity. It is concluded that iron deficiency in treated PV does not give increased whole blood viscosity.
对11例真性红细胞增多症（PV）患者进行了研究，这些患者接受了放血治疗且未补充铁剂。研究开始时，6例患者已缺铁，5例患者从正常铁状态随访至缺铁状态。通过血清铁蛋白、红细胞原卟啉、平均红细胞体积和平均红细胞血红蛋白来研究铁状态。在固定红细胞体积分数为44%时，全血粘度与这些变量中的任何一个均无相关性。缺铁期间和正常铁状态期间的平均全血粘度没有差异。即使缺铁数月后，全血粘度也没有增加。得出的结论是，接受治疗的PV患者缺铁不会导致全血粘度增加。
