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[通过向大鼠肾内注射解脲脲原体实验获得的结石]

[Calculi experimentally obtained in the rat by intrarenal injection of Ureaplasma urealyticum].

作者信息

Clerc M, Bebear C, Goursolle M, Clerc M, Aparicio M

出版信息

Ann Biol Clin (Paris). 1984;42(4):277-81.

PMID:6497071
Abstract

Male Sprague Dawley rats have been contaminated with Ureaplasma urealyticum (by injection in their kidney of a 10(8) C.C.U. suspension of micro-organisms of human origin). They produce urinary tract stones similar to the humans ones and composed of struvite crystals (NH4MgPO4, 6H2O). It is concluded that such a model is a very good tool to develop new research on struvite lithiasis.

摘要

雄性斯普拉格-道利大鼠已被解脲脲原体污染(通过向其肾脏注射10⁸ 色氨酸单位的人类来源微生物悬液)。它们会产生与人的结石相似且由鸟粪石晶体(NH₄MgPO₄·6H₂O)组成的尿路结石。得出的结论是,这样的模型是开展关于鸟粪石结石病新研究的非常好的工具。

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