Grenabo L, Brorson J E, Hedelin H, Pettersson S
Urol Res. 1985;13(4):195-8. doi: 10.1007/BF00261823.
To study the concrement-forming ability of Ureaplasma urealyticum in the urinary tract, viable and heat-killed ureaplasmas as well as urease and non-urease-producing bacteria were inoculated into the bladder in rats. Viable ureaplasmas, in contrast to heat-killed, caused the formation of bladder stones with a frequency corresponding to urease-producing bacteria (Proteus mirabilis). It was not possible to reculture the inoculated ureaplasmas from the urinary tract. Non-urease producing microorganisms (Escherichia coli and Mycoplasma hominis) only occasionally induced stone formation. The results indicate that U. urealyticum can initiate stone formation, a property that appears to be associated with the urease activity of the organism.
为研究解脲脲原体在尿路中形成结石的能力，将活的和解脲脲原体以及产脲酶和不产脲酶的细菌接种到大鼠膀胱中。与热灭活的解脲脲原体相比，活的解脲脲原体导致膀胱结石形成的频率与产脲酶细菌（奇异变形杆菌）相当。无法从尿路中再次培养出接种的解脲脲原体。不产脲酶的微生物（大肠杆菌和人型支原体）仅偶尔诱导结石形成。结果表明，解脲脲原体可引发结石形成，这一特性似乎与该生物体的脲酶活性有关。
